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2011;6(5):e19351

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Ginsenoside Rg1 can maintain iron-regulated protein homeostasis by increasing the expression of ferritin heavy chain and decreasing the expression of ferritin light chain (FTL) in natural oligodendrocytes (OLs) to resist lipid peroxidation stress in oligodendrocytes, thus playing a neuroprotective role ( Glial cells can store iron ions and release them when needed

Although insulin resistance (IR) plays a central role in metabolic diseases, in the liver, insulin- or substrate-driven de novo lipogenesis (DNL) promotes triglyceride accumulation through multiple complex regulatory mechanisms, including specific transcription factors, regardless of whether IR is primary or not